MILESTONE: Ailux enters into an AI licensing agreement with UCB for biologics discovery

Illuminating Biologics Discovery with AI

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PURPOSE

Ailux represents a groundbreaking approach that synergizes the strengths of AI, wet lab, and proprietary data to drive biologics discovery.

Our AI-powered platforms empower partners to achieve greater R&D success on the path toward the clinic.

VIRTUAL TOUR

Technology

World-leading biologics AI models powered by a massive, proprietary biologics dataset

EXPLORE OUR TECHNOLOGY

01 AI ENGINES
02 WET LAB
03 DATABASE

Model

protein complex structures to inform candidate selection and engineering.
Generate

developable biologics sequences with specified profile.
Predict

key properties to prioritize candidates without making them.

A state-of-the-art wet lab underpins our advanced AI models and one-stop solutions for partners.

Proprietary biologics database tailor-made for AI

AtlaX

Public dataset

Data size

Granularity

Label-Free

Qualitative

Quantitative

Seq

Binder

Develop-ability

K_D

Epitope

Trend line

Bubble size proportional to cost of data

01 AI ENGINES

Model protein complex structures to inform candidate selection and engineering.
Generate developable biologics sequences with specified profile.
Predict key properties to prioritize candidates without making them.

02 WET LAB

A state-of-the-art wet lab underpins our advanced AI models and one-stop solutions for partners.

03 DATABASE

Proprietary biologics database tailor-made for AI

AtlaX

Public dataset

Data size

Granularity

Label-Free

Qualitative

Quantitative

Seq

Binder

Develop-ability

K_D

Epitope

Trend line

Bubble size proportional to cost of data

APPLICATIONS

Addressing key bottlenecks in biologics discovery

HOW WE DELIVER VALUE

HARD TARGETS

GPCR

pMHC
High-homology

NEXT-GEN ENGINEERING

Super humanization

pH sensitivity

Affinity
modulation

Developability

Species
cross-reactivity

RAISE THE BAR

Repertoire NGS

Single B cell
screening

Display libraries

Epitope-specific

Lead
amplification

ADVANCED MODALITIES

ADC	Mini-protein/peptide

news & events

Explore our upcoming news & events

January 9, 2025

UCB partners with Ailux Biologics, a Division of XtalPi, on Biologics AI Platform

December 20, 2024

AET US 2024 | Trilux Antibody Discovery, Hit Expansion, and Affinity Modulation via Active Learning

November 21, 2024

PEGS Europe 2024 | AI-Powered Integrated Antibody Discovery and Multi-Objective Engineering

PARTNERSHIP

Are you ready to push the boundaries of what’s possible? We are here to help you tackle difficult targets and optimize critical leads

Partner with us

Case Study

Tapping into a greater search space for more quality hits using AI.

Immune Repertoire Analysis

In silico screening of millions of antibody sequences in the immune repertoire

K+

VL Clonotypes

K+

VH Clonotypes

Animals

NCS Datasets

M+

Unique VL Sequences

M+

Unique VH Sequences

Results and Insights

XploreSeq^TM Identifies Hits with High Accuracy

XploreSeq^TM routinely sequences millions of BCRs and identifies hits with high confidence (see figure). In this project, XploreSeq predicted 717 binders, from which 48 were randomly chosen for expression and testing. 66.7% (32/48) were confirmed to be binders, and only 18.6% (6/32) binders overlap with hybridoma hits.

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100 Chestnut Street, Somerville, MA 02143

尊龙凯时

Illuminating Biologics Discovery with AI

PURPOSE

Ailux represents a groundbreaking approach that synergizes the strengths of AI, wet lab, and proprietary data to drive biologics discovery.

Our AI-powered platforms empower partners to achieve greater R&D success on the path toward the clinic.

Technology

World-leading biologics AI models powered by a massive, proprietary biologics dataset

Model

Generate

Predict

A state-of-the-art wet lab underpins our advanced AI models and one-stop solutions for partners.

Proprietary biologics database tailor-made for AI

AtlaX

Public dataset

Label-Free

Qualitative

Quantitative

A state-of-the-art wet lab underpins our advanced AI models and one-stop solutions for partners.

Proprietary biologics database tailor-made for AI

AtlaX

Public dataset

Label-Free

Qualitative

Quantitative

APPLICATIONS

Addressing key bottlenecks in biologics discovery

news & events

Explore our upcoming news & events

UCB partners with Ailux Biologics, a Division of XtalPi, on Biologics AI Platform

AET US 2024 | Trilux Antibody Discovery, Hit Expansion, and Affinity Modulation via Active Learning

PEGS Europe 2024 | AI-Powered Integrated Antibody Discovery and Multi-Objective Engineering

PARTNERSHIP

Case Study

Tapping into a greater search space for more quality hits using AI.

Immune Repertoire Analysis

In silico screening of millions of antibody sequences in the immune repertoire

VL Clonotypes

VH Clonotypes

Animals

NCS Datasets

Unique VL Sequences

Unique VH Sequences

Results and Insights

XploreSeqTM Identifies Hits with High Accuracy

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Explore

XploreSeq^TM Identifies Hits with High Accuracy